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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK1
All Species:
31.21
Human Site:
S320
Identified Species:
52.82
UniProt:
P28482
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P28482
NP_002736.3
360
41390
S320
L
E
Q
Y
Y
D
P
S
D
E
P
I
A
E
A
Chimpanzee
Pan troglodytes
XP_510921
379
43006
T337
L
E
Q
Y
Y
D
P
T
D
E
P
V
A
E
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_860750
375
42862
S335
L
E
Q
Y
Y
D
P
S
D
E
P
I
A
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q63844
380
43048
T338
L
E
Q
Y
Y
D
P
T
D
E
P
V
A
E
E
Rat
Rattus norvegicus
P63086
358
41257
S318
L
E
Q
Y
Y
D
P
S
D
E
P
I
A
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_989481
368
41924
S328
L
E
Q
Y
Y
D
P
S
D
E
P
V
A
E
A
Frog
Xenopus laevis
P26696
361
41238
S323
L
E
Q
Y
Y
D
P
S
D
E
P
V
A
E
A
Zebra Danio
Brachydanio rerio
NP_878308
369
42057
T329
L
E
Q
Y
Y
D
P
T
D
E
P
V
A
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40417
426
49103
G383
L
E
Q
Y
Y
D
P
G
D
E
P
V
A
E
V
Honey Bee
Apis mellifera
XP_393029
371
42705
A322
L
E
Q
Y
Y
D
P
A
D
E
P
V
A
E
E
Nematode Worm
Caenorhab. elegans
P39745
444
50644
G391
L
E
Q
Y
Y
D
P
G
D
E
P
V
C
E
E
Sea Urchin
Strong. purpuratus
NP_999813
369
42176
D326
L
E
Q
Y
Y
D
P
D
D
E
P
V
K
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39024
376
42833
N336
L
A
P
L
H
D
I
N
E
E
P
V
C
V
R
Baker's Yeast
Sacchar. cerevisiae
P16892
353
40754
N316
L
Q
T
Y
H
D
P
N
D
E
P
E
G
E
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78
N.A.
96
N.A.
83.4
99.1
N.A.
N.A.
97.2
95.8
92.1
N.A.
67.8
81.9
64.4
79.4
Protein Similarity:
100
85.4
N.A.
96
N.A.
89.2
99.4
N.A.
N.A.
97.5
97.2
94.5
N.A.
74.6
86.7
70.9
84.5
P-Site Identity:
100
80
N.A.
100
N.A.
80
100
N.A.
N.A.
93.3
93.3
86.6
N.A.
80
80
73.3
73.3
P-Site Similarity:
100
93.3
N.A.
100
N.A.
93.3
100
N.A.
N.A.
100
100
100
N.A.
86.6
93.3
80
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.6
49.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
65.4
66.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
73.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
0
0
0
0
8
0
0
0
0
72
0
43
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% C
% Asp:
0
0
0
0
0
100
0
8
93
0
0
0
0
0
0
% D
% Glu:
0
86
0
0
0
0
0
0
8
100
0
8
0
93
36
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
15
0
0
0
0
8
0
0
% G
% His:
0
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
22
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
100
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
93
0
0
0
100
0
0
0
8
% P
% Gln:
0
8
86
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
0
0
0
0
0
0
0
36
0
0
0
0
0
0
0
% S
% Thr:
0
0
8
0
0
0
0
22
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
72
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
93
86
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _